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Inflammatory breast cancer stage iv

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Last Updated 05 February, Health Conditions. Similar Topics. How do You Get Cancer? Cancer Causing Foods. Same Category.
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Metastatic breast cancer

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Treatment of Inflammatory Breast Cancer

Background: Inflammatory breast cancer IBC is a rare but aggressive carcinoma characterized by severe erythema and edema of the breast, with many patients presenting in advanced metastatic disease. The "inflammatory" nature is not due to classic immune-mediated inflammation, but instead results from tumor-mediated blockage of dermal lymphatic ducts. In the present work, we investigated immune parameters in peripheral blood of metastatic IBC patients to determine whether cellular components of the immune system are altered, thereby contributing to pathogenesis of the disease. Methods: Flow cytometry-based immune phenotyping was performed using fresh peripheral blood from 14 stage IV IBC patients and compared to 11 healthy age-similar control women. Immunohistochemical analysis of tumor biopsies demonstrated moderate to high expression of PD-1 in Abstract Background: Inflammatory breast cancer IBC is a rare but aggressive carcinoma characterized by severe erythema and edema of the breast, with many patients presenting in advanced metastatic disease.
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Inflammatory Breast Cancer

Additional tests may be necessary to determine whether your cancer has spread to your lymph nodes or to other areas of your body. Not everyone needs every test, so your doctor will select the most appropriate tests based on your particular situation. Your doctor uses information from these tests to assign your cancer a stage.
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Metastatic breast cancer, also known as stage IV breast cancer, is the most advanced form of breast cancer 3. If breast cancer is not diagnosed and treated early, it can spread to nearby organs or enter the bloodstream and spread to distant organs in a process known as metastasis. Once breast cancer has turned metastatic, the disease is usually incurable. Only 1 to 3 percent of patients with metastatic breast cancer recover from the disease, notes the California Breast Cancer Research Program.
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